Successful Treatment of Toenail Fungus with Laser in Japan

Some doctors in Japan has succeeded in proving that laser treatment can cure toenail fungus. Two patients suffering from fungal infections on her toenails had been successfully treated with laser therapy. Although the oral antifungal agents have been shown to cure this nail disease effectively, the drug has many weaknesses, such as cause many side effects on the liver and kidneys. In addition, nail fungus pills also can not be used by certain populations such as children, mothers who are pregnant, elderly, or people who suffer from systemic disease. The findings of researchers in Japan proved that the laser can be a treatment option if patient’s condition did not allow an oral antifungal.

One of patients which are successfully treated with laser is a 80-year-old woman. She was suffering from toenail fungus for 3 years. Because it’s old age, doctors could not give an oral antifungal medication. So, Doctors gave Lamisil topical to kill fungus that infects her toenails. However, these topical treatments can not rid toenail fungus. Microscopic examination still showed fungal hyphae on the surface of the nail. The second patient was a woman aged 31 years. She is suffering from toenail fungus since she was a teenager. For more than 10 years, the fungus in her toenails were not successfully treated. This fungal infection causes yellowish toenail discoloration. Initially, she was consumed sporanox to cure these fungal infections. However, this oral treatment was discontinued because the woman complained of pain in the abdomen.

How is toenail fungus treatment process using laser?
Before irradiated with laser, nail patients were given urea ointment and ALA methyl ester cream. Several hours later, the laser beam irradiation performed. Both patients complained of pain during irradiation, but the pain is tolerable and disappeared after a day. After 6 to 7 times irradiation, toenail fungus have been successfully treated. Nails look more beautiful. After microscopic examination and culture, the fungus was not found. In fact, toenail fungus is also no recurrence after several months. Given these findings, we could consider laser treatment to cure toenail fungus.

Reference:
Watanabe D, et al. Successful Treatment of Toenail Onychomycosis With Photodynamic Therapy. 2008. Arch Dermatol 144(1):19-21.

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3 Responses to “Successful Treatment of Toenail Fungus with Laser in Japan”

  1. Mary Berry Says:

    Hello,
    I live in san jose ca and my associate and I have found a low level cold laser process that totally eradicated toenail fungus in 99% of the 140 patients we have seen. This is after 1 treatment. There is no pain because it is cold laser. I will be doing official research and publish soon
    Mary Berry



  2. paul kinsinger MD Says:

    I invented a topical product that is sold at 42 Walgreens and 120 other grocery and running shoe stores in Illinois and Indiana called Dr Pauls Piggy Paste. Its ingredients include vinegar and thymol (the active in listerine) I welcome the readers to check out my website as the product can be ordered on line. I live by word of mouth and the product does in fact “play in Peoria”.Stop wasting time soaking in water based solutions or applying the ” ” that is currently sold and try a product that was tested in my physicians’s office for a year before I found an FDA approved manufacturer. I found the product solves the ugly thick toenail problem 70-80% of the time when used daily and covered by a band aid in 12-16 weeks(which is the amount in one tube).Thats the same as lasar which is $900-1000. What should you try first? I welcome all inquiries about this future national brand. Dr Paul



  3. David Swanson DPM Says:

    Onychomycosis has been associated with about 200 species of Dermatophytes, yeast, Saprophytes, and rarely Actinomycetales. Just like in anti-bacterial treatments, effective treatment is based upon the organism being susceptible to the treatment. Dermatophytic infections occur more frequently in younger patients, while saprophytic infections occur more frequently in older patients. Treatments also fail because the chemical does not reach the infective organisms deep under the nail plate. Dermatophytes cause a white discoloration of the nail while sparophytes are typically yellow, tan, brown, or black. Few chemicals will kill saprophytes. Penlac, ketoconazole, itraconazole, fluconazole and possibly 40% uric acid have demonstrated anti-saprophytic activity. Laser treatments have difficuly reaching the root of the nail.



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