Lamisil Treatment for Toenail Fungus
Lamisil, which in generic name known as terbinafine, has been shown to be quite effective given orally for the treatment of toenail fungus. Lamisil is allylamine that is highly active against dermatophytes but less active against yeasts. It inhibits squalene epoxidase, a key enzyme for the synthesis of ergosterol which important , so it can kill fungi. This drug is used to treat infections caused by fungus that affect the fingernails or toenails.
Recommended oral dosage is 250 mg daily for 6 weeks for fingernail infections and 12 weeks for toenail fungal infections. One tablet given daily for 12 weeks achieves a cure rate of up to 90% for nail fungus and is more effective than griseofulvin (grisovin) or itraconazole (sporanox). Lamisil oral pills are also used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old. Adverse effects are rare, consisting primarily of stomach upset and headache. Before receiving lamisil for toenail fungus, you will be monitored closely with periodic laboratory evaluations for liver functions.
Beside used as oral medication, Lamisil are also available as 1% creams and other forms for the topical treatment of dermatophytosis such as toenail fungus due to the dermatophyte Tinea unguium, to be applied on a twice-daily dosing schedule. Adverse effects include local irritation, burning sensation, and erythema. You should avoid contact lamisil creams with mucous membranes such as mouth and nose.