Fluconazole is one of oral medications which can be used for curing toenail fungus. Fluconazole is an antifungal agents from azole groups. The antifungal activity of fluconazole can help in treating nail fungus because it is reducting ergosterol synthesis by inhibition of fungal cytochrome P-450 enzymes. It has higher oral bioavailability than itraconazole (sporanox) and ketoconazole.

Fluconazole also has fewer toxic effect on lever and better gastrointestinal tolerance than other azoles, so it can be used for aggressive dosing in a variety of fungal infections. But, fluconazole (diflucan) is not specific toenail fungus medicine. It is drug of choice in the treatment of cryptococcal meningitis because it displays a good cerebrospinal fluid penetration. Fluconazole is the agent most commonly used for the treatment of vagina or mouth yeast infections, which medically termed as mucocutaneus candidiasis.
To treat vagina and mouth yeast infections, you need daily dose of 100 mg fluconazole. But, alternate-day doses is sufficient to help you in getting rid of dermatophyte infections such as nail fungus. Alternate-day doses means you take drug every two day. For more informations on using fluconazole as medicine for toenail fungus, you should have to consult with your family doctor.

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