Oral Lamisil Pills to Treat Nail Fungus
Currently, lamisil is the standard treatment for fungal Trichophyton rubrum infections on nail beds, which more often known as nail fungus.
However, the standard treatment for nail fungus that has been used requires a very large cost of medical insurance. Therapy needs oral lamisil taken daily for 3 months.
The manufacturer recommends 250 mg of terbinafine (lamisil) every day for 12 weeks. Recommendations from factory have been approved by the U.S. Food and Drug Administration. Means, every patient who suffered from nail fungus must buy 84 lamisil pills. Price 30 pills terbinafine 250 mg on the market approximately $ 150. Means, to treat fungal infections is needed about $ 450. The high cost of treatment has led some doctors from Miami to study which lamisil treatment is most effective in curing nail fungus.
They compared the results of group therapy patients given lamisil 250 mg per day for 7 consecutive days every month, every 2 month, every 3 month, and every 4 months for 1 year. Treatment outcomes were also compared with the standard treatment of daily terbinafine for 3 month. More »
Black Toenails
Black toenails can be caused by excessive formation of melanin pigments. Toenail discoloration is found in some circumstances, such as pinta diseases, vitamin B12 deficiency, malignant melanoma skin cancer, and Peutz-Jegher syndrome. Besides above circumstances, toenail fungus can also cause discoloration of the nail.
Fungal infection Candida albicans and Blastomyces dermatitis often causes black toenails. Junction Nevi can also be the cause of this nail disorder. Toe nail color changes in Cushing’s syndrome are also common. This is caused by an increase in the hormone MSH (Melanin Stimulating Hormone). More »
Undecylenic Acid for Curing Nail Fungus
Undecylenic acid is organic fatty acid which can be used for curing nail fungus. This is a natural substance which is derived from natural castor oil. It has been FDA approved as treatment for fungal infections and dandruff. Recent studies have shown that the combination of this acid with some other substance that could be a new generation of nail fungus topical treatment. This medication not only helps your nails to grow healthy, but also kill the existing mold.
Other studies show how the mechanism of Undecylenic acid in killing the fungus. To prove the ability to kill bacteria from these materials, the researchers use candida albicans. One possible mechanism for Undecylenic acid is the inhibition of enzymes involved in lipid metabolism. Cerulenin, an inhibitor of fatty acid biosynthesis, inhibited germ tube formation, and phospholipase D1 has been implicated in morphogenesis. It is not the first antifungal agent shown to inhibit morphogenesis at sub lethal concentrations. Nystatin, amphotericin B, and triazoles have been shown to inhibit fungal morphogenesis. More »
